Hello everyone,
I was wondering if someone has some experience with using the CLC BIO genomics workbench to call indels in ion torrent PGM data? Did you encounter a lot of false positives in homopolymer regions?
I heard that it might be a good idea to remap your data with different settings (different penalty values for gap extension, gap opening, ...) before you search for indels? Any thougths on that?
I was wondering if someone has some experience with using the CLC BIO genomics workbench to call indels in ion torrent PGM data? Did you encounter a lot of false positives in homopolymer regions?
I heard that it might be a good idea to remap your data with different settings (different penalty values for gap extension, gap opening, ...) before you search for indels? Any thougths on that?
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