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Old 09-03-2017, 03:07 AM   #1
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Location: Oxford

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Question CGHcall analysis on tetraploid samples: single deletion = 1 or 2 copies loss?

Hi all,

I'm using QDNAseq package for chromosomal aberrations analysis and then CGHcall for bins calling. I have samples with different ploidy so I run CGHcall separately on group of samples which are tetraploid. I know for diploid sample, single deletion is 1 copy loss - just wondering for a tetraploid sample, when single deletion is called - does it still mean 1 copy loss or 2 copies loss instead in tetraploid sample?

Many thanks,

Last edited by EvelynLau; 09-03-2017 at 04:55 AM.
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cgh, copynumber, copynumberanalysis, qdnaseq

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