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  • Computational Research Scientist in cancer bio (Weill Cornell Medical College, NYC)

    The Neuberger Berman Lung Cancer Research Center in the Department of Cardiothoracic Surgery at Weill Cornell Medicine, located in New York City, is looking for a Computational Research Scientist to design and carry out bioinformatics and statistical analyses to investigate biological processes underlying cancer biology.

    This position offers a unique opportunity to combine rich clinical and high-throughput sequencing data to investigate cancer biology and quantify the effects of state-of-the-art treatment regimens. We are looking for motivated and curious PhD-level candidates to explore multi-modal datasets to characterize changes on transcriptional, protein, metabolomic, and epigenomic levels in relation to demographic and other medical information.

    As a Computational Research Specialist in the Department of Cardiothoracic Surgery, you will actively participate in generating new hypotheses and be responsible for designing and carrying out integrative bioinformatics and biostatistical analyses on data from a variety of next generation sequencing (NGS) experimental platforms, including whole genome sequencing, exome sequencing, RNA-seq, ribosomal profiling, and epigenomics methods, in addition to metabolomics and proteomics datasets.

    As a successful candidate for this staff position, you will be intimately familiar with best practices and the current literature in the NGS analysis field, and fluent with commonly used tools (e.g., the Tuxedo suite, samtools, STAR, GATK, and especially R), reference sequence databases (e.g., RefSeq, UCSC, Ensembl, dbSNP), and public data repositories (e.g., cBio Portal, Oncomine). You will be comfortable analyzing both high-throughput sequencing and clinical data, and be familiar with various statistical and machine learning techniques including classification and predictive modeling (e.g., Bayesian classifiers, SVMs, clustering techniques, time-to-event models), as well as functional analysis approaches (e.g., gene expression analysis, network analysis).

    You will be proficient in working in a Linux computing environment, and automating tasks using scripting languages such as bash, python, perl, or ruby. A firm understanding of clinical biostatistics is a plus.

    To apply for this position, please email your CV in .pdf format along with a cover letter to:

    Murtaza S. Malbari, M.S.
    Neuberger Berman Lung Cancer Research Center
    Department of Cardiothoracic Surgery
    Weill Cornell Medicine
    New York, NY 10065
    [email: [email protected]]

    Weill Cornell Medicine is located in Manhattan, New York, immediately adjacent to the Sloan Kettering Institute and Rockefeller University. This Tri-institutional campus includes several hundred principal investigators, and has one of the highest densities of biomedical scientists in the world. This rich scientific environment provides unique and unparalleled research training opportunities, including seminars given by scientific leaders from throughout the world, opportunities for collaborations, exposure to diverse research programs, and highly sophisticated core facilities.

    The Department of Cardiothoracic Surgery at Weill Cornell Medicine is a recognized leader in heart, lung and esophagus surgery, conducting a robust clinical trials program to evaluate the effectiveness of new treatments and medications that have the potential to improve the management of patients with heart, lung, and esophageal disease.

    Weill Cornell Medicine is an equal opportunity, affirmative action educator and employer.

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