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Old 10-21-2013, 04:12 PM   #1
Bioinformatics Engineer
Location: University of Cambridge, UK

Join Date: Jun 2010
Posts: 14
Default DNaseR - DNase-seq digita genomic footprinting in R

Dear Bioinformatics community,

DNase-seq has been used to measure chromatin accessibility in a given
tissue or cell type on a genome-wide scale. In addition to DNaseI
hypersensitivite sites (DHSs), short regions of protected nucleotides
known as footprints can be detected, indicating transcription factor
binding ocuppancy events.

DNaseR, a new package for DNase I footprinting analysis of DNase-seq
has been released in the current version Bioconductor. Devel
version is at:

DNaseR aims to detect protein binding footprints in DNase-seq data
from reads in BAM standard aligment format.

Best regards,
Pedro Madrigal
Research Associate
Wellcome Trust Sanger Institute
Wellcome Trust Genome
Cambridge, CB10 1SAUK
Pedro Madrigal
pmad is offline   Reply With Quote

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