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Question: Is there another new methylated DNA base out there?
Hi everyone,
I am new in the field and have been reading some papers on DNA methylation. I realized that the focus in the past 20 years has really been on the methylated cytosine. I have several questions and would appreciate your insights:
1. Has anyone in the past ruled out the possibility of other methylated bases e.g. methylated guanine, adenine or thymine as possible epigenetic markers?
2. When was methylated cytosine first found? How was it discovered?
3. Do you all think that there might be more DNA methylations that are yet to be discovered?
Sorry if these questions sound ignorant to you, I am trying to learn a new field. Thank you!
Scotty
I am new in the field and have been reading some papers on DNA methylation. I realized that the focus in the past 20 years has really been on the methylated cytosine. I have several questions and would appreciate your insights:
1. Has anyone in the past ruled out the possibility of other methylated bases e.g. methylated guanine, adenine or thymine as possible epigenetic markers?
2. When was methylated cytosine first found? How was it discovered?
3. Do you all think that there might be more DNA methylations that are yet to be discovered?
Sorry if these questions sound ignorant to you, I am trying to learn a new field. Thank you!
Scotty
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