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Average coverage for miRNAseq analysis for mouse/human ? warrenemmett Bioinformatics 0 09-30-2013 09:43 AM

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Old 03-07-2014, 07:48 PM   #1
thejustpark
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Default Average number of microRNA target sites for human genes?

Dear community,

Since some of you are very experienced scientist, I would like to ask for some expertise:
Can you tell me how many miR binding sites genes have on average?
My research totally depends on number of miR binding sites, and I took targetScan's estimates, which gives me around 20~30 on average.
But my boss thinks that number is too many for genes, and wants me to prove the number using literature.
And he wants a direct evidence, like a distribution figure of the miR target site number, for example.

But I can't find one, after trying hard for a couple of weeks.
If you have ever seen this kind of literature, can you please let me know of them and save me?
I know it can read as a personal request, but please understand my situation.*

Help will be greatly appreciated.
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Old 03-11-2014, 06:38 AM   #2
TiborNagy
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Some literature:
http://www.ncbi.nlm.nih.gov/pubmed/23936243
http://www.ncbi.nlm.nih.gov/pubmed/23826142
http://www.ncbi.nlm.nih.gov/pubmed/18388938
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Old 03-11-2014, 06:42 AM   #3
thejustpark
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Thanks a lot, TiborNagy.
I am reading it, and it seems helpful!
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