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Bioinformatics Scientist
Updated: January 5, 2019
Job ID: 214497
Status: Full-Time
Regular/Temporary: Regular
Location: Silver Spring, MD, United States
HJF is seeking a Bioinformatics Scientist to support the Military HIV Research Program (MHRP) located at the Walter Reed Army Institute of Research (WRAIR) in Silver Spring, Maryland. HJF provides scientific, technical and programmatic support services to MHRP.
The Host Genomics Section at MHRP (https://www.hivresearch.org/our-scie...smi-thomas-phd) is looking for an enthusiastic, energetic and motivated individual to join our research effort investigating the functional consequences of human genetic, transcriptome, epigenetic and microbiome variation on HIV-1 and emerging diseases pathogenesis. The candidate will be responsible for designing, leading, and carrying out integrative analyses of these ‘omics’ data, to elucidate cellular pathways and networks that are associated with immune responses to infectious diseases.
Responsibilities:
1. The candidate will implement analysis workflows to facilitate omics analysis, and pursue bioinformatics analyses in collaborations within our research group and other groups/clinicians within MHRP.
2. Workflows will include quality control, sequence alignment and annotation, gene expression determination, statistical testing, visualization and pathway analysis.
3. Generate, analyze, and manage large and computationally complex datasets.
4. Perform project-specific laboratory-based research.
5. Author scientific publications based on both research findings and data analysis results derived from employing standard and novel analysis methodologies.
6. Prepare technical reports, summaries, and SOPs.
7. Train and manage junior staff.
8. Present data and issues/problems at weekly section meetings.
9. Perform other duties as assigned.
Required Knowledge, Skills, and Abilities: Extensive experience with next generation sequencing computational and analytical tools. The ability to construct high-throughput analysis pipelines for omics data, and to integrate with in-house databases. Must be highly motivated to solve biological problems, and have experience analyzing large-scale and high-throughput genomics data (e.g., experience with one or more of: exome sequencing, ChIP-Seq, methyl-Seq or RNA-Seq data). The candidate should have good knowledge of at least one scripting language for handling large-scale data (e.g., Python, Perl), and one programming language for implementing computational models and algorithms (R, Matlab, Python, C/C++). Must be an enthusiastic, self-directed, and communicative team player; be able to troubleshoot technical procedures; and possess excellent writing and communication skills. Must be able to work independently as indicated by an ability to publish papers.
Minimum Education/Training Requirements: Ph.D. in Bioinformatics, computational biology or a related scientific discipline.
Minimum Experience: 2-4 years of related research experience in analyzing and interpreting human datasets.
Background: Must have lived in the US 3 out of the past 5 years; eligible to pass a NACI background. This position is only open to US citizens and permanent residents.
Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, addresses, education, and credentials, a criminal background check, drug screening, and a department of motor vehicle (DMV) check.
HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
Updated: January 5, 2019
Job ID: 214497
Status: Full-Time
Regular/Temporary: Regular
Location: Silver Spring, MD, United States
HJF is seeking a Bioinformatics Scientist to support the Military HIV Research Program (MHRP) located at the Walter Reed Army Institute of Research (WRAIR) in Silver Spring, Maryland. HJF provides scientific, technical and programmatic support services to MHRP.
The Host Genomics Section at MHRP (https://www.hivresearch.org/our-scie...smi-thomas-phd) is looking for an enthusiastic, energetic and motivated individual to join our research effort investigating the functional consequences of human genetic, transcriptome, epigenetic and microbiome variation on HIV-1 and emerging diseases pathogenesis. The candidate will be responsible for designing, leading, and carrying out integrative analyses of these ‘omics’ data, to elucidate cellular pathways and networks that are associated with immune responses to infectious diseases.
Responsibilities:
1. The candidate will implement analysis workflows to facilitate omics analysis, and pursue bioinformatics analyses in collaborations within our research group and other groups/clinicians within MHRP.
2. Workflows will include quality control, sequence alignment and annotation, gene expression determination, statistical testing, visualization and pathway analysis.
3. Generate, analyze, and manage large and computationally complex datasets.
4. Perform project-specific laboratory-based research.
5. Author scientific publications based on both research findings and data analysis results derived from employing standard and novel analysis methodologies.
6. Prepare technical reports, summaries, and SOPs.
7. Train and manage junior staff.
8. Present data and issues/problems at weekly section meetings.
9. Perform other duties as assigned.
Required Knowledge, Skills, and Abilities: Extensive experience with next generation sequencing computational and analytical tools. The ability to construct high-throughput analysis pipelines for omics data, and to integrate with in-house databases. Must be highly motivated to solve biological problems, and have experience analyzing large-scale and high-throughput genomics data (e.g., experience with one or more of: exome sequencing, ChIP-Seq, methyl-Seq or RNA-Seq data). The candidate should have good knowledge of at least one scripting language for handling large-scale data (e.g., Python, Perl), and one programming language for implementing computational models and algorithms (R, Matlab, Python, C/C++). Must be an enthusiastic, self-directed, and communicative team player; be able to troubleshoot technical procedures; and possess excellent writing and communication skills. Must be able to work independently as indicated by an ability to publish papers.
Minimum Education/Training Requirements: Ph.D. in Bioinformatics, computational biology or a related scientific discipline.
Minimum Experience: 2-4 years of related research experience in analyzing and interpreting human datasets.
Background: Must have lived in the US 3 out of the past 5 years; eligible to pass a NACI background. This position is only open to US citizens and permanent residents.
Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, addresses, education, and credentials, a criminal background check, drug screening, and a department of motor vehicle (DMV) check.
HJF is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
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