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Old 05-30-2018, 02:47 AM   #1
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Location: the UK

Join Date: May 2018
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Default Biclustering methods

Hi everyone,

I am new to bioinformatics and new to this forum. Hope that I could learn more about bioinformatics here.

I am now trying to identify subtypes of cancer with my RNA-Seq data. I did a lot of reading and it looks like that biclustering could give a better results than just hierarchical clustering. However, the biclustering methods that perform well in categorisation (e.g. spectral clustering) have only been applied to microarray data in publications. Is there any recommendation on which biclustering method I should use for RNA-Seq data that performs reasonably good in terms of categorising subtype of cancer?
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