Hi,
I am new to next generation sequencing analysis. So I need to map my 8 ChIP-seq samples(transcription factor) and I don't want to use galaxy.
So I was wondering what will be differences whether I use bowtie2 or bwa? And what kind of parameters should I use for aligning my reads?
P.S: Out of curiosity and since our department has DNAstar license, I would be grateful if you tell me your views on mapping with DNAstar?
I am new to next generation sequencing analysis. So I need to map my 8 ChIP-seq samples(transcription factor) and I don't want to use galaxy.
So I was wondering what will be differences whether I use bowtie2 or bwa? And what kind of parameters should I use for aligning my reads?
P.S: Out of curiosity and since our department has DNAstar license, I would be grateful if you tell me your views on mapping with DNAstar?
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