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  • NovaSeq 6000

    We recently acquired a NovaSeq in August (we had been using HiSeq 2500's previously) Being a brand new instrument and the cost alone, I had anticipated no problems. However, it went down in September (less than a month in operation) with CE engine compute problems and now again just recently with power supply issues to a computing board. Repairs have been slow resulting in down times for a week or more, which is detrimental for a Clinical sequencing lab, such as ours. I am curious, has anyone else had problems with the NovaSeq system?

    Chad

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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