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  • CASIM: Assembly Using Synteny information

    Is there a program that allows you to use the genome sequences of closely related species to inform the assembly a the genome of a new species, while allowing for a potentially significant loss of synteny

    e.g. between two closely related species of bacteria that could have undergone significant rearrangement and gene loss/gain?

  • #2
    you'll get binding and a PCR product for one allele, but won't get a PCR product for the alternate allele. In practice, non-specific amplification can sometimes make the results difficult to interpret.
    somatodrol
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