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Old 06-27-2012, 09:15 AM   #1
Location: USA-Iowa

Join Date: Mar 2009
Posts: 13
Default Covaris M220

Has anyone purchased and used a Covaris M220 yet? I am wondering specifically for use in shearing for 454 FLX Plus Rapid Library preps. I have a several projects coming up with large numbers of RL+ libraries and am starting to look for an alternative to nebulization.

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Old 06-27-2012, 04:05 PM   #2
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Location: San Diego, CA

Join Date: Sep 2009
Posts: 105


The Covaris M220 is a new personal DNA fragmentation system launched at the AGBT this year.
I think it will be a great idea for you to evaluate the M220 in your lab with your DNA samples. Covaris at the moment has a 14 day no questions asked evaluation without the need to submit a PO or leave a credit card. You can find out more at
The installation and setup for use is very simple and easy. It takes less than 10 minutes to install, and the instrument is ready to use within 5 minute of the installation.
The optimized settings for shearing sizes of 150bp to 5kb can be found at

Thank you

Senior Scientist
Covaris Inc

Last edited by Hamid; 06-28-2012 at 10:39 AM.
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