Hi,
has anybody experience with combining following two datasets:
1X coverage of 454 reads (backbone)
30X coverage of solexa reads
background: we are talking about a non sequenced plant genome. So I would use the 1x 454 reads as a backbone for the solexa reads to perform a de novo assembly.
Question: is a 1X 454 coverage in this case a waste of money or a real help in the assembly? Somebody experience with this?
has anybody experience with combining following two datasets:
1X coverage of 454 reads (backbone)
30X coverage of solexa reads
background: we are talking about a non sequenced plant genome. So I would use the 1x 454 reads as a backbone for the solexa reads to perform a de novo assembly.
Question: is a 1X 454 coverage in this case a waste of money or a real help in the assembly? Somebody experience with this?
Comment