Innovative Solutions vs AMPure

suefo · 10-14-2011, 11:56 AM

Today we were visited by folks from Innovative Solution who were promoting their PCRClean and DNA SizeSelect purification kits. They claim that side-by-side with AMPure, we would get far better results with their kits. The PCRClean will remove any fragments less than 120 bp. And their DNA SizeSelector-454 are designed to retain greater than 500 bp. Has anyone tried these products yet? And if so, can you provide feedback?

Website to view products: http://stores.alinebio.com/-strse-DN...Categories.bok

Heisman · 10-14-2011, 02:02 PM

I get excellent results from Ampure so I find it hard to believe you can get far better results from any other system. I'll be interested to hear about this too.

ECO · 10-14-2011, 06:22 PM

It has a higher range of size selection (above 1kb), but it more challenging to use for automation as the beads settle out of the less viscous solution.

I have limited experience with it, seems like it could be beneficial for larger insert gel-free protocols.

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10-14-2011, 11:56 AM	#1
suefo Member Location: Ann Arbor, MI Join Date: Jul 2011 Posts: 36	Innovative Solutions vs AMPure Today we were visited by folks from Innovative Solution who were promoting their PCRClean and DNA SizeSelect purification kits. They claim that side-by-side with AMPure, we would get far better results with their kits. The PCRClean will remove any fragments less than 120 bp. And their DNA SizeSelector-454 are designed to retain greater than 500 bp. Has anyone tried these products yet? And if so, can you provide feedback? Website to view products: http://stores.alinebio.com/-strse-DN...Categories.bok Last edited by suefo; 10-14-2011 at 11:58 AM.

10-14-2011, 02:02 PM	#2
Heisman Senior Member Location: St. Louis Join Date: Dec 2010 Posts: 535	I get excellent results from Ampure so I find it hard to believe you can get far better results from any other system. I'll be interested to hear about this too.

10-14-2011, 06:22 PM	#3
ECO --Site Admin-- Location: SF Bay Area, CA, USA Join Date: Oct 2007 Posts: 1,358	It has a higher range of size selection (above 1kb), but it more challenging to use for automation as the beads settle out of the less viscous solution. I have limited experience with it, seems like it could be beneficial for larger insert gel-free protocols.