Helicos sequencing: Single-Molecule DNA Sequencing of a Viral Genome

eldfors · 04-04-2008, 08:36 AM

http://www.sciencemag.org/cgi/conten...t/320/5872/106

Single-Molecule DNA Sequencing of a Viral Genome
Timothy D. Harris, Phillip R. Buzby, Hazen Babcock, Eric Beer, Jayson Bowers, Ido Braslavsky, Marie Causey, Jennifer Colonell, James DiMeo, J. William Efcavitch, Eldar Giladi, Jaime Gill, John Healy, Mirna Jarosz, Dan Lapen, Keith Moulton, Stephen R. Quake, Kathleen Steinmann, Edward Thayer, Anastasia Tyurina, Rebecca Ward, Howard Weiss, and Zheng Xie (4 April 2008)

Science 320 (5872), 106. [DOI: 10.1126/science.1150427]
The M13 viral genome has been resequenced by a single-molecule method that allows simultaneous sequencing of 280,000 DNA strands of 25 bases with 100 percent coverage.

ECO · 04-04-2008, 09:19 AM

Thanks for the post! Discussion is beginning in the thread in the Helicos Forum:

http://seqanswers.com/forums/showthread.php?t=191

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04-04-2008, 08:36 AM	#1
eldfors Junior Member Location: Finland Join Date: Mar 2008 Posts: 2	Helicos sequencing: Single-Molecule DNA Sequencing of a Viral Genome http://www.sciencemag.org/cgi/conten...t/320/5872/106 Single-Molecule DNA Sequencing of a Viral Genome Timothy D. Harris, Phillip R. Buzby, Hazen Babcock, Eric Beer, Jayson Bowers, Ido Braslavsky, Marie Causey, Jennifer Colonell, James DiMeo, J. William Efcavitch, Eldar Giladi, Jaime Gill, John Healy, Mirna Jarosz, Dan Lapen, Keith Moulton, Stephen R. Quake, Kathleen Steinmann, Edward Thayer, Anastasia Tyurina, Rebecca Ward, Howard Weiss, and Zheng Xie (4 April 2008) Science 320 (5872), 106. [DOI: 10.1126/science.1150427] The M13 viral genome has been resequenced by a single-molecule method that allows simultaneous sequencing of 280,000 DNA strands of 25 bases with 100 percent coverage.

04-04-2008, 09:19 AM	#2
ECO --Site Admin-- Location: SF Bay Area, CA, USA Join Date: Oct 2007 Posts: 1,358	Thanks for the post! Discussion is beginning in the thread in the Helicos Forum: http://seqanswers.com/forums/showthread.php?t=191