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Old 11-15-2010, 05:24 AM   #1
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Location: London

Join Date: Jun 2009
Posts: 5
Default Covaris fragmentation with 100bp reads

We have previously been shearing our samples to 100-400bp using Covaris fragmentation when preparing our 76bp paired end libraries. We are now planning to use a HiSeq with 100bp paired end libraries - doea anybody know if altering the shearing would make a difference?
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