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Old 07-04-2011, 04:42 AM   #1
harshinamdar
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Default exome and transcriptome

what is the difference between exome and transcriptome ? how does their assembly differ ?
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Old 07-04-2011, 11:31 PM   #2
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is it transcriptome is always time specific whereas exome is whole rna count irrespective of the time?
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Old 07-05-2011, 06:23 AM   #3
Eric Fournier
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The transcriptome consists of all that is transcribed, ie all RNA species including mRNA, miRNA, tRNA, lncRNA, etc. It is usually studied through samples of RNA. You can get the basic idea by reading this: http://en.wikipedia.org/wiki/Transcriptome

The exome refers to the protein coding portion of the genome. It is usually studied through samples of DNA. I'd recommend reading this article for an example of exome sequencing and its applications: http://www.ncbi.nlm.nih.gov/pmc/arti...1/?tool=pubmed
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