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Old 11-08-2010, 01:30 PM   #1
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Default Chromosomes segregation for sequencing


We would like to segregate chromosomes of a eukaryotic genome. For example, several institutes are sequencing different human chromosomes. How did they segregate only their target chromosomes? Should I do it before or after sequencing?


Last edited by thsuk1; 11-09-2010 at 05:00 AM.
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Old 11-09-2010, 06:27 AM   #2
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Try this thread Chromosomal isolation & sequencing.

Depending on the organism, why you want to focus on a chromosome & such, either just sequencing the whole genome & focusing on your chromosome in the post informatics may be simpler OR you may want to use a capture method on the regions of interest.
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