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Old 11-19-2012, 09:06 AM   #1
lweinert
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Location: cambridge

Join Date: Nov 2012
Posts: 2
Default University of cambridge - research associate computational biologist

UNIVERSITY OF CAMBRIDGE
DEPARTMENT OF VETERINARY MEDICINE

RESEARCH ASSOCIATE COMPUTATIONAL BIOLOGIST


Salary: 27,578.00 to 35,938.00
Limit of Tenure: 24 months

Applications are invited for the post of Computational Biologist, to start 1 February 2013 or as soon after.

You will be part of a team in the Bacterial Infection Group working on the virulence of four important bacterial respiratory tract pathogens of pigs: Streptococcus suis, Haemophilus parasuis, Actinobacillus pleuropneumoniae and Mycoplasma hyopneumoniae. The project is supervised by Professor Duncan Maskell and Dr. Dan Tucker, and is being undertaken in collaboration with groups at Imperial College London, London School of Hygiene and Tropical Medicine, the Royal Veterinary College, Huazhong Agricultural University and the Wellcome Trust Sanger Institute, with Pfizer as an industrial partner. It is a BBSRC-funded LoLa project with the aim of developing a novel diagnostics platform and a multivalent vaccine to facilitate control of these economically important porcine pathogens.

The post-holder will be responsible for the analysis of data derived from Transposon Directed Insertion-site Sequencing (TraDIS), an Illumina sequencing-based functional genomics technology that is being applied to identify genes required for pathogen survival on an in vitro organ culture (IVOC) model of the pig respiratory tract. They will also investigate the evolutionary history, population structure and potential diagnostic markers of the above species through analysis of genome sequences obtained from hundreds of strains of each organism.

The applicant will have, or shortly expect to be awarded, a PhD in computational biology, microbiology, genetics, molecular biology or a related discipline, and should have experience of working with large data sets derived from high throughput sequencing technologies. They should be familiar with common software tools for genome assembly, annotation and phylogenetic analysis. They will also have experience of programming in a language such as Perl or Python, and of statistical methods and software packages such as R.

For informal enquiries please contact Professor Duncan Maskell, e-mail: [email protected].

Further particulars and CHRIS/6 application form can be downloaded from http://www.vet.cam.ac.uk/news.
Applications should be sent for the attention of Melissa Large, Department of Veterinary Medicine, Madingley Road, Cambridge CB3 0ES. Applications can be made via email to [email protected], quoting the reference in the subject.

Closing date: 2nd January 2013
Interviews will be held on 22nd January 2013
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