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  • NovaSeq 6000

    We recently acquired a NovaSeq in August (we had been using HiSeq 2500's previously) Being a brand new instrument and the cost alone, I had anticipated no problems. However, it went down in September (less than a month in operation) with CE engine compute problems and now again just recently with power supply issues to a computing board. Repairs have been slow resulting in down times for a week or more, which is detrimental for a Clinical sequencing lab, such as ours. I am curious, has anyone else had problems with the NovaSeq system?

    Chad

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin


    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...
    Today, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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