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Old 04-09-2009, 11:11 AM   #1
tfcheng
Junior Member
 
Location: MD

Join Date: Apr 2009
Posts: 3
Default How to compare two WIG files??

Hi all,
Sorry if this is an faq question... I been doing chip-seq for a while, I perform chip and other people in the lab do seq, actually. So I don't really know what's going on in the black box. After GA-II, I have 23 WIG files that can be uploaded to UCSC genome browser for me to examine. And that was just preliminary exp, now I have control vs. experimental chip-seq, and I need to extract the difference between them, I am not exactly a bioinformatics guy, so I come up here and ask for help in terms of the software that I can use, thank you!!

TFC
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Old 08-28-2013, 02:23 AM   #2
pmad
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Location: University of Cambridge, UK

Join Date: Jun 2010
Posts: 14
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HI TFC,

the Bioconductor package NarrowPeaks

http://bioconductor.org/packages/rel...rrowPeaks.html

can handles comparison of bigWig files, but you will need to covert WIG to bigWig using the wigToBigWig utility (http://genome.ucsc.edu/goldenPath/help/bigWig.html)

Hope that helps,
P.
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