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Old 08-08-2008, 06:02 AM   #1
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Default PubMed: ZOOM! Zillions Of Oligos Mapped.

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ZOOM! Zillions Of Oligos Mapped.

Bioinformatics. 2008 Aug 6;

Authors: Lin H, Zhang Z, Zhang MQ, Ma B, Li M

MOTIVATION: The next generation sequencing technologies are generating billions of short reads daily. Resequencing and personalized medicine need much faster software to map these deep sequencing reads to a reference genome, to identify SNPs or rare transcripts. RESULTS: We present a framework for how full sensitivity mapping can be done in the most efficient way, via spaced seeds. Using the framework, we have developed software called ZOOM, which is able to map the Illumina/Solexa reads of 15X coverage of a human genome to the reference human genome in one CPU-day, allowing two mismatches, at full sensitivity. AVAILABILITY: ZOOM is freely available to non-commercial users at CONTACT:,,

PMID: 18684737 [PubMed - as supplied by publisher]

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Old 08-11-2008, 02:09 PM   #2
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Default Dead link?

Has anyone been able to try this software? I am getting a 404 error from the link.
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Old 08-11-2008, 02:23 PM   #3
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We've been having a great conversation about it in another thread:

It's not yet available, but should be shortly.

The more you know, the more you know you don't know. —Aristotle
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Old 08-21-2008, 07:52 AM   #4
Janine Voyer
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I wanted to let everyone know that the ZOOM demo is now available. Please send me an email at to request a 30 day free demo.

Please also check out our benchmarks for ZOOM at: http://www.bioinformaticssolutions.c...benchmarks.php for Illumina/Solexa data. The benchmarks for ABI SOLiD data will be coming soon.
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