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#1 |
Junior Member
Location: Boston Join Date: Oct 2013
Posts: 3
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I want to download seqs of a pfam, build an hmm, and search a genome for the hmm.
The wellcome sanger site is a bit confusing to me. I can see there are 250 or so sequences total in the pfam, but it also says there are 4 different architectures. What does this mean? 4 "types" in this pfam? Does this mean I want to hmm search 4 times? Which sequences map to which architectures? Any help appreciated. |
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#2 |
Member
Location: India Join Date: Aug 2010
Posts: 78
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The hmmer tool, is your best bet for searching a nucleotide sequence with a hmm model.
For a detailed appreciation of hmm model use and lot of examples please refer to the hmmer 3 documentation hope this helps, -- pg |
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