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Old 12-21-2010, 03:40 AM   #1
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Default ChIP-Seq: Arabidopsis paves the way: genomic and network analyses in crops.

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Arabidopsis paves the way: genomic and network analyses in crops.

Curr Opin Biotechnol. 2010 Dec 15;

Authors: Ferrier T, Matus JT, Jin J, Riechmann JL

Arabidopsis genomic and network analyses have facilitated crop research towards the understanding of many biological processes of fundamental importance for agriculture. Genes that were identified through genomic analyses in Arabidopsis have been used to manipulate crop traits such as pathogen resistance, yield, water-use efficiency, and drought tolerance, with the effects being tested in field conditions. The integration of diverse Arabidopsis genome-wide datasets in probabilistic functional networks has been demonstrated as a feasible strategy to associate novel genes with traits of interest, and novel genomic methods continue to be developed. The combination of genome-wide location studies, using ChIP-Seq, with gene expression profiling data is affording a genome-wide view of regulatory networks previously delineated through genetic and molecular analyses, leading to the identification of novel components and of new connections within these networks.

PMID: 21167706 [PubMed - as supplied by publisher]

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