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If I have some point mutation data, snv and indel, and want to check whether these mutation are recorded in cosmic. Which file on the cosmic ftp should I use?
for now, there are two vcf files on cosmic ftp which should be most convenient to use. However, because the vcf file only contain mutation with length less than 10bp, these two vcf files do not include all the information for cosmic.
for other files, such as CosmicCodingMuts_v60_190712.vcf.gz, some mutation in this file does not have genome coordinate information, which gives some hurdle to compare with other data.
Will please give me some advices for which files should I use if I want to get all the snv/indel mutation information (genome coordinate, mutated allele sequence) for cosmic?
for now, there are two vcf files on cosmic ftp which should be most convenient to use. However, because the vcf file only contain mutation with length less than 10bp, these two vcf files do not include all the information for cosmic.
for other files, such as CosmicCodingMuts_v60_190712.vcf.gz, some mutation in this file does not have genome coordinate information, which gives some hurdle to compare with other data.
Will please give me some advices for which files should I use if I want to get all the snv/indel mutation information (genome coordinate, mutated allele sequence) for cosmic?