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  • VCF file / relationship between QUAL and DP fields

    Can someone explain to me if there is a relationship between QUAL en DP fields in a VCF file.

    If I understand well, a high DP value (coverage) does not exactly mean high quality?

    Thank you.

  • #2
    I assume that the QUAL field is dependent on quality scores of base calls of the reads that map to a particular locus. Of course it really depends on what software made the VCF file, but I imagine that the DP field has an impact on the QUAL field.

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