Hello all. I am trying to use SOAPec KmerFreq_AR to filter and correct my reads before assembly. It seems to work great when the option -s is not set. The -s flag sets the space seed and turns on the spaced kmer option. The issue is that it crashes with "Segmentation Fault". No other error output. Does anyone have any ideas on how to troubleshoot this issue? I have tried joining and posting something on the SOAP-Group, but for some reason the group is not approving my messages. I have seen some posts online with similar problems, but no resolutions. Has anyone got this to work?
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...-
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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