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  • A problem with Elastic net + Cox regression

    I was trying to perform elastic net + cox regression in R using the glmnet package. The problem is that my data is around 100 individuals with ~100k features and the model is too big for R to store in a matrix. Although the glmnet package can use sparse matrix for the model unfortunately it does not support it with Cox regression.

    Anyone knows of another tool I can use (I am not locked in R, it was just the only tool I found)? I read that I can use an SVM (support vector machine) but I still need to calculate the model. I am looking for any tool (R, Matlab, stand alone application) that can perform elastic net + cox regression on a big model. Furthermore, maybe you know how to calculate this big model as a stand alone output so I can use it in an SVM?

  • #2
    For reference cross-posted: https://www.biostars.org/p/176689/

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    • #3
      I am sorry, I did not know that it is against the rules to post in multiple forums the same question. Not to make another post on this: I will mention if on the other forum the question in answered.
      Last edited by Anastaziel; 02-11-2016, 04:13 PM.

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      • #4
        Originally posted by Anastaziel View Post
        I am sorry, I did not know that it is against the rules to post in multiple forums the same question.
        No it is not against the rules so don't worry.

        I included the link so people can see if your question has been answered on Biostars before they compose a lengthy response (if one was needed) here.

        You can help by coming back and posting a closure if your question is answered on Biostars.

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        • #5
          I was able to fix my problem. I was using a wrong test case and my model was becoming too big. Using the example from glment.pdf fixes the issue.

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