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Methylation Study EpiBrass Epigenetics 5 11-08-2013 12:53 AM

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Old 08-18-2015, 01:45 PM   #1
lancelothk
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Location: cleveland

Join Date: Sep 2013
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Default partial methylation/intermediate methylation

For single CpG site, what may cause the partial methylation/intermediate methylation in BS-seq data?
What I know are:
1. allelic methylation difference in diploid cell.
2. sequencing/bisulfite error (after trim lower quality bps, filter out low bisulfite conversion rate reads)
3. Inter-cell variation for mix cells sample.

How to distinguish this from other type?
Is there any literature about this topic?

Thanks.
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