We have RNAseq variant data for 12 tumour samples. We don't have matched non-tumour samples (to filter out germline mutations), so would like to use the 1000 Genomes Project data to filter out such SNPs instead.
Any pointers? The RNAseq variant data is currently in 12 VCF files, one for each tumour sample. So far all the analysis has been performed with R, so an R-based solution would be ideal.
Thanks for any help.
Any pointers? The RNAseq variant data is currently in 12 VCF files, one for each tumour sample. So far all the analysis has been performed with R, so an R-based solution would be ideal.
Thanks for any help.