Does anyone know of a good reference/webpage that describes what is actually going on inside of GATK's Unified Genotyper? The only detail that I could find was a link from their 'unified genotyper' page to a dense mathematical paper by Heng Li (http://www.broadinstitute.org/gsa/wi...0/Samtools.pdf). I was looking for something in between this document by Li and their user manual. Thanks.
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.
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Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...-
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