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Old 02-15-2012, 09:30 AM   #1
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Location: Boston

Join Date: Feb 2012
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Default Job Opportunity - Partners HealthCare Boston, MA - Senior Bioinformatician, PCPGM

For additional details and to apply, please click the following link:

About Our Organization:
Partners HealthCare is an integrated health care system founded by Brigham and Women's Hospital and Massachusetts General Hospital. In addition to its two academic medical centers, the Partners system includes community and specialty hospitals, community health centers, a physician network, home health and long-term care services, and other health-related entities. Partners is one of the nation's leading biomedical research organizations and a principal teaching affiliate of Harvard Medical School. Partners HealthCare is a not-profit organization. We have opportunities in Finance, Information Systems, Human Resources, and many other areas that work behind the scenes in support of the Partners mission.

Job Description:
The Partners HealthCare Center for Personalized Genetic Medicine (PCPGM) is a leader and innovator helping realize the promise of personalized medicine by accelerating the integration of genetic knowledge into clinical care. The PCPGM has an opening for a Senior Bioinformatician who will focus on continuously advancing the state of the art of research and clinical genetic testing. The PCPGM is tasked with translating the latest genetic discoveries into routinely orderable genetic tests that are used to improve clinical decision making for patients around the world. Fulfilling this mission requires us to transition technologies from the research to the clinical arena. The radical and sustained drop in physical sequencing costs is making this process increasingly dependent on bioinformatics.

The incumbent will deepen the PCPGM’s bioinformatics support surrounding a variety of instruments used in both research and clinical settings. The center hosts sequencing, genotyping, and microarray cores in addition to a clinical laboratory. The Senior Bioinformatician will assist in constructing software pipelines for next-generation sequencing (NGS) applications and in mining of clinical data. Assigned tasks will depend on the center’s priorities and may encompass responsibilities beyond those described here.

Training in computational biology in addition to a strong understanding of the principles of genetics is required. Strong programming skills are necessary for this position.

- PhD in Bioinformatics, or equivalent, as well as at least two years of full time experience in an academic or biotechnology industry lab; OR Masters degree with 5+ years of full time experience; OR strong computer science background (10+ years development experience) with significant exposure to bioinformatics tools and processes.
- Strong knowledge of Java, XML and Regular Expressions.
- Proficiency in Unix/Linux shell scripting, Perl or Python.
- Experience working with next-generation sequencing pipelines (variant detection, variant annotation, or genotype/phenotype correlation).
- Good knowledge of common NGS applications.
- Good knowledge and understanding of algorithms, data structures, and scientific programming.
- Good knowledge of SQL.
- Moderate knowledge of applied statistics.
- Ability to work in a Unix/Linux environment.
- Ability to manage multiple projects in a dynamic environment with changing priorities.
- Ability to work with other bioinformaticians with establishing realistic goals and deliver work on schedule.
- Strong interpersonal skills and ability to work as part of a diverse team, while contributing to a high-quality and respectful work environment.
- Excellent oral and written communication skills, with the ability to communicate effectively to colleagues and staff across multi-disciplinary areas.
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