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For some reason this information is not readily available. Just want to know who to give the nobel prize to.
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As usual, there is not a simple answer.
Frequently Rollin Hotchkiss is credited, because he was the first to describe "Epi-cytosine" as a distinct, but chemically very similar base to cytosine. (see Fig. 2)
However he established no link to epigenetics and also did not investigate the exact chemical structure of "Epi-Cytosine". The identification as 5mC was achieved by Waldo Cohn in 1951 .
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM -
Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...03-22-2024, 06:39 AM
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