Does someone know any program for in silico enzyme digestion. I am a web lab scientist , need to do a computational simulation for whole genome enzyme digestion. I need a program which has the input option for genome, enzyme, the resulting fragment size range, also whether the fragment is unique. The output file are something like the Bed file like format with chr, start, end, and fragment size etc. It will be great that it can also give a distribution plot for the fragment. Thanks a lot!!!! I will be really appreciate.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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