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  • getting genotypes with oligo package

    Hi, I have genotyped samples from Affy6.0 platform using crlmm algorithm
    from Oligo and I am facing difficulties in interpretation. I am trying
    to match the SNP calls from crlmm with their respective alleles. I would appreciate any comments and help.
    Given a SNP has A and B allele, is it that A is always a major allele
    and B is always a minor allele or is it that the allele A and B are
    alphabetically assigned; the first alphabet (A,T,G,C) gets assigned as
    A allele and the next alphabet is assigned as B allele?
    I used the code provided in the oligo package help. I would greatly obtain a result in a tabulated file like below:
    NA06985.CEL NA06991.CEL
    SNP_A-1507972 TT TC
    SNP_A-1510136 AG GG

    Thanks

  • #2
    I suspect that A would be the major allele and B the minor allele, but I don't know for sure.

    Try posting your question on the Bioconductor mailing list:
    The Bioconductor project aims to develop and share open source software for precise and repeatable analysis of biological data. We foster an inclusive and collaborative community of developers and data scientists.

    Comment


    • #3
      Thanks for response. I have posted this question on the Bioconductor mailing list and I 'm waiting for an answer ....

      Comment

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