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The NextPrep-Mag™ Urine cfDNA Isolation Kit is an automation-friendly kit designed to extract DNA from urine, using a magnetic bead format. The rapid procedure can be completed in only 30 minutes and does not require a vacuum manifold. Using the kit, sufficient cfDNA is recovered from urine sample volume ranging from less than 1 mL to more than 20 mL, to allow robust construction of libraries for targeted or whole genome sequencing. The cfDNA isolated using this kit can be used for applications including studies of circulating fetal DNA and cancer diagnostic-related liquid biopsy studies.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM