I'm familiar with (but have not used) ParseSNP (http://www.proweb.org/parsesnp/), a tool that calculates the effect (frame shift, truncation, etc.) of nucleotide mutations (indel, substitution) on genes, given the gene model. However, I'd like to do this on a genome-wide scale: load in a long list of mutations, and return protein effects if the mutation is within a gene. And I don't really think the people hosting ParseSNP would appreciate me bombing their servers by submitting entire chromosomes (of Arabidopsis thaliana)! Maybe it wouldn't be a problem ... I'll ask them.
But, in the meantime, are there more convenient, fast tools, for which the source is available, that do this? Any suggestions or advice would be appreciated.
Thanks,
~Joe
But, in the meantime, are there more convenient, fast tools, for which the source is available, that do this? Any suggestions or advice would be appreciated.
Thanks,
~Joe
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