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Old 01-11-2010, 12:01 AM   #1
gavin.oliver
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Default Comparison of NGS analyser tech info

Hi all,

I'm sure this question has been asked before so maybe I'll just be pointed to an old thread, but:

Basically I'm looking for an up-to-date comparison of the major NGS analysers' main technical info - perhaps in table format?

Thanks in advance,

Gavin
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Old 01-12-2010, 12:31 AM   #2
gavin.oliver
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Does noone have any ideas on this?

It would be aprticularly useful to get an idea of the cost per run of the major contenders (454, Solid, Solexa).

Thanks in advance
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Old 01-12-2010, 05:01 AM   #3
gavin.oliver
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I found this comprehensive comparison:

http://genomics.ucr.edu/about/report...1207_Table.pdf

Can someone advise whether any of the info is very outdated? I think the document is from March 2008.

Thanks
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Old 01-12-2010, 05:36 AM   #4
ffinkernagel
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there's http://www.clcngs.com/2008/12/ngs-platforms-overview/ which has some about everything but the price per base.
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Old 01-12-2010, 05:46 AM   #5
gavin.oliver
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Really useful, thanks

I'm a newbie so forgive me for asking - Do the Solid 1 and 2 and Solexa GA and GA II represent old (outdated) models?
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Old 01-12-2010, 05:57 AM   #6
ffinkernagel
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Not being immensely familiar with them myself, I know the GAIIx is an upgrade to the GAII machine, and I presume the GA is an older machine.

Please note that the list always contains the 'largest run' - ie. you can run a GAIIx with only 36 bp which makes a single run considerably faster (but in the end I guess is about the same/a little less throughput, but lower latency)
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Old 01-28-2010, 06:04 PM   #7
VanessaS
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Quote:
Originally Posted by gavin.oliver View Post
Really useful, thanks

I'm a newbie so forgive me for asking - Do the Solid 1 and 2 and Solexa GA and GA II represent old (outdated) models?

I can only speak about the SOLiD, 1 and 2 are old versions. They have come out with the 3, the 3+, and in a month or two will bring out 4. By the end of the year (we shall see) 4hq. Times are a changin'!
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Old 01-29-2010, 02:14 AM   #8
gavin.oliver
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I'm a bit confused about the accuracies. Some sources suggest Illumina is more accurate than ABI and some suggest the opposite. The specs on their respective websites would seem to suggest that the SOLiD is currently the most accurate when running at full capacity.
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Old 01-29-2010, 11:26 PM   #9
avilella
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Default Next Generation Sequencing spreadsheet

Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?k...hQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>

Last edited by avilella; 01-30-2010 at 04:22 AM.
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Old 01-30-2010, 02:36 AM   #10
Xi Wang
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Quote:
Originally Posted by avilella View Post
Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?k...hQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.
Oh my god, I can't access google spreadsheet from China..
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Old 03-19-2010, 02:41 AM   #11
KevinLam
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Quote:
Originally Posted by avilella View Post
Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?k...hQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>
Nice work!
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Old 03-19-2010, 07:04 AM   #12
RockChalkJayhawk
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Default Cost per run of different platforms

I'm trying to get a rough idea of how much it costs every time you turn on one of these instruments. Can you all help approximate? I know it vaires on application, so a range is acceptable.

I know the HiSeq is ~$20K (10K if just one flow cell), but what about
GAIIe:
SOLiD4:
SOLiD PI:

?
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Old 03-22-2010, 06:36 PM   #13
ymc
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Quote:
Originally Posted by Xi Wang View Post
Oh my god, I can't access google spreadsheet from China..
That's why BGI set up shop in Hong Kong.
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Old 03-22-2010, 06:39 PM   #14
ymc
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Quote:
Originally Posted by avilella View Post
Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?k...hQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>
Is this really correct? I think on Illumina's official page, HiSeq 2000 is max 200Gb/run and GAIIx is max 50Gb/run.
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Old 03-22-2010, 06:40 PM   #15
Xi Wang
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Quote:
Originally Posted by ymc View Post
That's why BGI set up shop in Hong Kong.
So does google...
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Old 03-22-2010, 07:16 PM   #16
ymc
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Originally Posted by Xi Wang View Post
So does google...
Yeah, that too. But to stay on topic, 100 HiSeq 2000s will be in HK. This will make HK the sequencing capital of the world!
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Old 03-23-2010, 02:29 AM   #17
Chipper
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Quote:
Originally Posted by ymc View Post
Is this really correct? I think on Illumina's official page, HiSeq 2000 is max 200Gb/run and GAIIx is max 50Gb/run.
http://www.genomeweb.com/sequencing/...new-instrument
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Old 03-23-2010, 05:36 AM   #18
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Quote:
Originally Posted by Chipper View Post
Do we really need 60x coverage for genome sequencing???
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Old 03-23-2010, 08:54 AM   #19
nickloman
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Quote:
Originally Posted by ymc View Post
Yeah, that too. But to stay on topic, 100 HiSeq 2000s will be in HK. This will make HK the sequencing capital of the world!
Who in HK is buying 100 HiSeq instruments? I did read the press release that BGI are buying 128 HiSeqs but they are based in Shenzhen, which is in mainland China?
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Old 03-23-2010, 08:57 AM   #20
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Oh, I've re-read the press release and I see that they are installing the machines in Hong Kong Science Park:
http://www.genomics.cn/en/news_show....pe=show&id=500
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