Hi,
I'm new to exome sequencing data analysis, and I'm puzzled by the fact that the tool packages I have (GATK, samtools) only output the CNV locations instead of the true copy numbers for each exome, or each gene. Is there any tool that can give me the copy numbers for an exome or a gene?
Besides, if I have two samples, can I directly compare their copy numbers, or I should apply some sort of normalization first?
Thank you very much for the help!
Jie
I'm new to exome sequencing data analysis, and I'm puzzled by the fact that the tool packages I have (GATK, samtools) only output the CNV locations instead of the true copy numbers for each exome, or each gene. Is there any tool that can give me the copy numbers for an exome or a gene?
Besides, if I have two samples, can I directly compare their copy numbers, or I should apply some sort of normalization first?
Thank you very much for the help!
Jie
Comment