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The NEXTFLEX® unique dual index barcodes (UDIs) are ready-to-ship, 384 barcoded adapters that provide data security and accuracy for Illumina® sequencing. These UDIs are carefully designed to mitigate index hopping or spread of signal known to occur on patterned flow cells. These barcodes are also compatible with PCR-free workflows. Incorporating UDIs into your NGS workflow addresses problems regarding index and sample mis-assignment, run-to-run sample carryover, and sample crosstalk.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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