Vector NTI for windows 10?

[Tlexander]

Hi All,

Any workable version of Vector NTI for windows 10?

By the way, which one is the best choice to replace vector NIT, Genome Compiler or Benchling, or some other more powerful software?

Thanks.

[GenoMax]

All Vector NTI versions (Suite/Express) work on Win 10, though all require purchase of a license. There are no free desktop options (AFAIK) to obtain database functionality included in Vector (there are cloud based alternatives as you note).

[vpontis]

Hey Tlexander and GenoMax,

Benchling does pretty much everything that Vector NTI does but for free and in the browser. Benchling being in the browser means that it works on all operating systems and you can easily switch from computer to computer.

It also comes with a full lab notebook to plan and track your experiments.

Disclaimer: I am a software engineer at Benchling. Let me know if there is anything from Vector NTI which we don't have in Benchling.

Signup via benchling.com/signup

[GenoMax]

@vpontis: What is the business model at benchling if you are making it available for free? I am sure the enterprise version has a cost but is that subsidizing free users? Is the "free" option limited in some way compared to the full version?

[vpontis]

@GenoMax

Our mission is to accelerate the pace of life science research, so we see putting a fully-featured experiment planning and DNA tool in academics hands for free as a central part of that.

As for our business plan, we make money selling private deploys of Benchling to enterprise companies. This includes features listed on our enterprise page (https://benchling.com/enterprise) but does not include much that an academic would want/need.

Let me know if you have any questions.

[Rutia]

Definitely Genome Compiler. The only free software tool which is a true all-in-one solution for researchers with an awesome visualization.

Initially, you can choose to work online or use the downloadable version (both are free).

You can import and manage your data inside it's cloud-based Materials Box, which allows you to access your data from anywhere you are (Genome Compiler is compatible with many file formats, including Vector NTI). The Materials Box contains parts and plasmids from a plethora of databases (Sigma, Addgene, Synberc, Lucigen...) as well as a direct import feature from NCBI and iGEM databases.

From there, you can conveniently design your sequences / cloning vectors, perform sequence alignments, design primers, design your cloning experiment using the intuitive wizards and more. In addition, you can use the integrated tools such as the RBS Calculator by Howard Salis to predict protein expression levels.

Another great tool is the sharing and collaboration tool, which makes it easy for you to share your projects with others, without their need to pay for a license. They can add comments / edit your project - depending on your permission. This feature makes the lab collaboration a lot easier.

Finally, when you finish your design, you can directly ask for a price quote from your DNA provider and order it seamlessly without any extra costs.

Good luck!