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Old 11-26-2014, 09:54 AM   #1
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Default VCF file / relationship between QUAL and DP fields

Can someone explain to me if there is a relationship between QUAL en DP fields in a VCF file.

If I understand well, a high DP value (coverage) does not exactly mean high quality?

Thank you.
cambyses is offline   Reply With Quote
Old 11-26-2014, 11:22 AM   #2
Location: Connecticut

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I assume that the QUAL field is dependent on quality scores of base calls of the reads that map to a particular locus. Of course it really depends on what software made the VCF file, but I imagine that the DP field has an impact on the QUAL field.
blakeoft is offline   Reply With Quote

coverage depth, quality

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