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  • Comparative genomics

    Hi everyone,
    I begin a new study in comparative genomics between two strains from same species (a reference strain and a new one freshly assembled and annotated). I need to find all the differences between the two chromosomal sequences, except SNPs. Up to now, I have used ACT to visualize the genomic alignment and I have listed all the differences manually. I can say for now that the majority of differences are caused by movement of insertion sequences (ISs).

    Now that I know the nature of the all differences between the two genomes, I want to use a web server to do the sames analyses that me, just to check the accuracy of my results

  • #2
    Just a little up. I have the same question.

    Comment


    • #3
      Originally posted by Jean_Guillaume777 View Post
      Hi everyone,
      I begin a new study in comparative genomics between two strains from same species (a reference strain and a new one freshly assembled and annotated). I need to find all the differences between the two chromosomal sequences, except SNPs. Up to now, I have used ACT to visualize the genomic alignment and I have listed all the differences manually. I can say for now that the majority of differences are caused by movement of insertion sequences (ISs).

      Now that I know the nature of the all differences between the two genomes, I want to use a web server to do the sames analyses that me, just to check the accuracy of my results
      Hi Jean,

      were you able to figure it out? Please share.

      Comment


      • #4
        Take a look to this page VISTA Tool. I sucessfully have recently compared two full steptococcus genomes. I eventually process the information that this service gave me to figure out the genes present in one strain that were missing in the other

        Comment


        • #5
          Thank you AntonioRFranco!

          I will try VISTA Tool for my genomic comparison.

          Comment

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