I am currently researching mutational signatures in Cancer genomes (see here for an explanation: http://cancer.sanger.ac.uk/cosmic/signatures). I am using the DeconstructSigs package in R to analyze the data I have available. I was just wondering, do there exist other software for performing the same task that are seen as better? I know of the existence of the SomaticSignatures package but am unclear whether it is any better or worse than DeconstructSigs.
Any advice would be greatly appreciated!
Any advice would be greatly appreciated!