I used edgeR to find differntially expressed genes of my RNA-seq data. I am little bit confused with one observation. A couple of genes are only turned on in my treatment group (ie 0 reads in my control group). But I got a particular value (for example 30) of fold change. What my confusion is, if there is no expression at all in my control group, how can edgeR give this value? Can anybody help me?
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Originally posted by Puva View PostI used edgeR to find differntially expressed genes of my RNA-seq data. I am little bit confused with one observation. A couple of genes are only turned on in my treatment group (ie 0 reads in my control group). But I got a particular value (for example 30) of fold change. What my confusion is, if there is no expression at all in my control group, how can edgeR give this value? Can anybody help me?
Hope this helps...
Dario
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