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Old 07-05-2011, 07:51 AM   #1
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Location: Boston, MA, USA

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Default Staff Scientist – NGS data analysis – Massachusetts General Hospital

Position: Computational Biology & Bioinformatics Staff Scientist
Institutions: Massachusetts General Hospital and Harvard Medical School, Boston, MA
Department: Center for Computational Discovery at the Massachusetts General Hospital Cancer Center
Reports To: Director of the Center for Computational Discovery
Salary: Commensurate with level of experience
Status: Full-time

The Center for Computational Discovery (CCD) collaborates with laboratories in the Cancer Center of the Massachusetts General Hospital to take high-throughput approaches (e.g., sequencing, microarray, functional screening, imaging) to answer applied and fundamental questions in cancer biology and medicine. We seek an expert in the analysis of Next Generation Sequencing (NGS) data.

Responsibilities will include:
  • Working collaboratively with multi-disciplinary teams to design experiments.
  • Analyzing the output of NGS runs for quality and biological meaning.
  • Contributing to the publication of results.
  • Developing and publishing new analytical methods, where needed.
  • Contributing to the CCD’s software libraries, which are written in R, C/C++, Python and SQL.

Experiments include (but are not limited to):
  • ChIP-seq
  • RNA-seq
  • Digital gene expression
  • Whole exome re-sequencing
  • Whole genome re-sequencing

Minimal qualifications:
  • 2+ years of post-doctoral work analyzing NGS data
  • Experience with a statistical programming language (e.g., Matlab, R)
  • Excellent teamwork/collaboration and interpersonal skills
  • Proficiency in written and spoken English
  • Good communication skills

Preferred qualifications:
  • Experience with a general programming language (e.g., Java, C/C++), a scripting language (e.g., Perl, Python) and SQL
  • Experience with cluster computing
  • Formal education in biology, statistics and computer science
  • Experience with multi-person software development

The position is open for immediate filling.

If interested, please email the following to Sridhar Ramaswamy (
  • A brief statement discussing why you are a strong candidate for this position.
  • Curriculum vitae listing education, qualifications, and experiences, including a list of scientific publications.
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