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Old 10-24-2010, 01:27 AM   #1
NGS specialist
Location: Malaysia

Join Date: Apr 2008
Posts: 249
Default Detection of Fusion Gene Events from RNASeq PE reads

Hi Everybody,

I am looking for the best strategy for finding gene fusion events in some human resequencing RNASeq paired-end reads.
At present there is one package I am aware of called DeFuse, however I think that tools such as BreakDancer, Breakway and Hydra-SV would be suitable for this task with some downstream operations.

I have my reads mapped to HG18 with novoalign in BAM format. Some pointers from people with experience would be great.

zee is offline   Reply With Quote
Old 10-24-2010, 07:48 PM   #2
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Location: Boston area

Join Date: Nov 2007
Posts: 747

You might also check out Trans-ABySS and FusionSeq

I haven't (yet) gotten experience with any of these.
krobison is offline   Reply With Quote
Old 05-12-2011, 10:14 PM   #3
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Location: china

Join Date: Apr 2011
Posts: 6

I think you can look this page :

there is a workflow for you
kissthefuture is offline   Reply With Quote

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