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  • Looking for comparative genomics tools for prokaryotes

    Hello! I'm looking for a sofrware that's able to compare the genomes between different subtypes of a specie(or multiply strains) and determine which genes are present in one subtype but not the other and if there are any mutations unique to each subtype. EDGAR seems perfect for this purpose, since it has the functions I need and has a large database, but it's an online tool. Can anyone suggest a software or command line tool that's able to achieve what EDGAR does, but can install locally? Thank you very much!

    Best,
    Ben

  • #2
    Consider using Mauve for this application.

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    • #3
      Thank you, I'll try it out!

      Best,
      Ben

      Comment


      • #4
        Corrigendum required for EDGAR paper, since EDGAR is NOT opensource!

        In their EDGAR paper published in the BMC Bioinformatics 2009, 10:154:
        http://www.biomedcentral.com/1471-2105/10/154

        they mention that this tool is licensed under the GNU GPL license (Is opensource) - see PDF of the paper, page 12, but since there is no link to EDGAR sources available on the EDGAR website, it is NOT opensource.

        If any part of EDGAR research was funded with the intention of making both sources of the tool(s) and service available online, than it must be revised, and either:

        1. Sources of all EDGAR pipeline components made available on github/bitbucket/etc to the general public.

        Or

        2. Funding of the original EDGAR grant revised/repaid back to the funding body.

        Originally posted by benZ2016 View Post
        EDGAR seems perfect for this purpose, since it has the functions I need and has a large database, but it's an online tool.
        Last edited by GenoMax; 05-05-2016, 04:13 AM. Reason: Fixed URL

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