Can anyone please explain the how the normalization is done for GC-content bias?
I read the papers but could not get the grasp of the statistical method used.
"Understanding mechanisms underlying human
gene expression variation with RNA sequencing"
Removing technical variability in RNA-seq data using
conditional quantile normalization
Thanks!
I read the papers but could not get the grasp of the statistical method used.
"Understanding mechanisms underlying human
gene expression variation with RNA sequencing"
Removing technical variability in RNA-seq data using
conditional quantile normalization
Thanks!