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Old 07-02-2014, 02:45 AM   #1
Location: Spain

Join Date: Nov 2013
Posts: 28
Default Mathematical fool


Well my problem is that I'm a Biologist and so I've got no much statistical or mathematical background to understand some procedures in R. (I'm working in differential expression of RNA-seq data nowadays). What should I read or do to help me through? Are there some specific books or lessons that could be useful for people like me?

Thank you in advance!
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Old 07-02-2014, 09:26 AM   #2
Devon Ryan
Location: Freiburg, Germany

Join Date: Jul 2011
Posts: 3,480

Read through the DESeq2 vignette (or that from edgeR or limma). In particular, they generally have test datasets so you can follow along with how an analysis works. Other than that, you might try taking a short course on RNAseq from one of the many companies that seem to be popping up to offer that.
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Old 07-07-2014, 04:36 AM   #3
Senior Member
Location: Budapest

Join Date: Mar 2010
Posts: 329

I am learn a lot from Coursera.
There is an article to help improving your skills:
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Old 07-08-2014, 05:27 AM   #4
Michael Love
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Location: Boston

Join Date: Jul 2013
Posts: 333

Rafael Irizarry and I put together the Data Analysis for Genomics class on edx.

Rafa's lectures (as well as all course content) are free to watch.

You could jump to the differential expression content in week 3, which covers statistical inference and linear models.

The lecture notes are here (still be polished up):
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Old 07-18-2014, 06:15 AM   #5
Location: Spain

Join Date: Nov 2013
Posts: 28

Thank you very much, all of you!

I think your advices and links will help me a lot
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